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Comprehensive genomic
biomarker results in 2 days

Fast, accurate treatment decisions for NSCLC patients

ASPYRE’s comprehensive lung panel simultaneously analyzes DNA and RNA from blood or tissue in a single assay, enabling straightforward, precise identification of all NCCN guideline recommended genomic biomarkers associated with approved targeted therapies for NSCLC.

Fast time to treatment

ASPYRE-Lung dramatically simplifies and accelerates the detection of actionable biomarkers, enabling you to identify targeted treatment options within days of diagnosis.

Reduced sample requirement

ASPYRE’s high sensitivity enables testing from tissue samples with as little as 10% tumor content, compared to 20% or 30% for most competing assays.

Actionable results

ASPYRE accelerates and simplifies analysis by eliminating the noise from genomic data, ensuring accuracy for the markers that are of interest, to enable more confident decision-making.

Ultra-sensitive

ASPYRE’s high sensitivity enables accurate biomarker analysis from blood or tissue, even from limited samples with low tumor content.

HubSpot Video

 

Biomarkers included in ASPYRE-Lung

ASPYRE-Lung enables the simultaneous analysis of 77 DNA mutations & 37 RNA fusions.

 

DNA

EGFR

Exon 18
  • G719A
  • G719S
  • G719C
Exon 19
  • Deletions
  • Insertions
Exon 20
  • T790M
  • S7681
  • C797S
  • Insertions
Exon 21
  • L858R
  • L861Q

BRAF

Exon 15
  • V600E

KRAS

Exon 2
  • G12A
  • G12C
  • G12D
  • G12F
  • G12R
  • G12S
  • G12V
Exon 2
  • G13A
  • G13C
  • G13D
  • G13R
  • G13S
Exon 3
  • Q61E
  • Q61H
  • Q61K
  • Q61L
  • Q61R

ERBB2

Exon 17
  • V659E
Exon 20
  • Insertions

RNA

ALK

RET

MET

NTRK1

NTRK2

NTRK3

ROS1

Featured resources & publications

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The ASPYRE technology

Read more about how the unique molecular biology behind ASPYRE overcomes the limitations of PCR and NGS to increase access to comprehensive biomarker testing.

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Ultra-sensitive molecular detection of gene fusions from RNA using ASPYRE

Gray et al, BMC Medical Genomics | (2022) 15:215
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Single-copy detection of somatic variants from solid and liquid biopsy

A-L. Silva et al, Scientific Reports | (2021) 11:6068



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Introducing ASPYRE-Lung

By simplifying the detection of genomic biomarkers from either tissue or blood, use of ASPYRE-Lung as a first-line diagnostic helps identify those NSCLC patients who will likely benefit from precision medicine in a fraction of the time and at a fraction of the cost of NGS.

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