- Supported by BlueYard Capital, Longwall Ventures and Agilent Technologies
- Funds to be used to bring technology to market, enabling a dramatic simplification of precision genetic testing to ensure many more cancer patients receive optimal diagnosis and therapy
- Initial focus on lung cancer, with the potential for broad application across the $15 billion cancer market for targeted therapy and patient monitoring
CAMBRIDGE, United Kingdom, Aug. 20, 2020 (GLOBE NEWSWIRE)—Biofidelity Ltd, the cancer diagnostics company, today announces the successful completion of a $12m Series A financing. The round was led by BlueYard Capital and backed by experienced investors including Longwall Ventures and Agilent Technologies, a global leader in life sciences and diagnostics.
Biofidelity’s disruptive technology combines fast, affordable, easy to interpret results, in order to dramatically simplify genetic testing while providing all the key benefits of next generation sequencing (NGS). The Company estimates that 95% of cancer patients are currently excluded from NGS due to high cost, complexity, and slow turnaround times. Biofidelity provides clinically actionable data based on ultra-sensitive detection of the markers recommended in cancer treatment guidelines, enabling oncologists to prescribe the right cancer drug at the right time to many more patients. Straightforward adoption on existing infrastructure is expected to greatly increase the number of laboratories able to offer superior cancer diagnostics.
Biofidelity is initially focusing on diagnosis of non-small cell lung cancer, with potential across a broad range of cancers as well as applications in the detection of resistance to therapy and disease recurrence.
In January, Biofidelity announced the successful completion of a study to detect key lung cancer mutations in collaboration with Agilent Technologies. The collaboration, using an assay developed by Biofidelity, demonstrated an improvement in sensitivity of 50 times that achieved with current FDA-approved PCR-based diagnostics. This matched the sensitivity of specialised NGS assays, which require error-correction technology, while providing a dramatic simplification of workflows from more than 100 steps to just four. Assays were performed using standard laboratory instrumentation, demonstrating the potential for straightforward adoption of Biofidelity’s panels in decentralised testing laboratories around the world.
The Series A funds will be used to accelerate the development and clinical validation of oncology panels for treatment selection and patient monitoring in oncology, and to bring these assays rapidly to market through direct sale, partnering and collaboration.
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